Pillsbury A, Chiew M, Bag S, et al. Adolescents and adults who have been incompletely vaccinated or do not have evidence of immunity to measles are recommended to receive measles-containing vaccine. Measles is spread by respiratory secretions, including by aerosols.19 It is infectious from the beginning of the prodromal period (typically 2 to 4 days before rash onset) and for up to 4 days after the rash appears.49 See Symptoms of measles. Measles virus. 2020 Aug;17(169):20200480. doi: 10.1098/rsif.2020.0480. Measles-mumps-rubella-varicella, Jacobsen SJ, Ackerson BK, Sy LS, et al. Changes to recommended age at which infants can receive the MMR vaccine. Low-dose systemic corticosteroid therapy includes: People receiving high-dose corticosteroids can receive MMR-containing vaccines after they have stopped corticosteroid therapy for at least 1 month (see Contraindications).27, Some experts suggest temporarily stopping lower doses of steroids 2–3 weeks before vaccination with live viral vaccines, if possible.20,27. A recent blood transfusion with washed red blood cells is not a contraindication to MMR or MMRV vaccines. Children with a personal or close family history of seizures or convulsions can receive MMR or MMRV vaccine. Measles is often a severe disease. Expand year-round vaccination efforts with these resources, videos, and tools. However, serological testing for measles immunity can be done: Alternatively, these people can receive MMR vaccine without serological testing. Communicable Diseases Intelligence 2016;40 Suppl:S1-70. See Recommendations and Adverse events. Western Pacific Surveillance and Response Journal: WPSAR 2016;7(4):1-9. doi:10.5365/wpsar.2016.7.1.010. If a child receives the 2nd dose of measles-containing vaccine early, they are considered to have completed their vaccination schedule. Measles-containing vaccine is recommended for: Measles-containing vaccine is recommended for children at 12  months of age as MMR (measles-mumps-rubella) vaccine, and at 18 months of age as MMRV (measles-mumps-rubella-varicella) vaccine. Measles can be transmitted in healthcare settings and infect staff and patients.4-7. (See Adverse events). Measles vaccine. Heywood AE, Gidding HF, Riddell MA, et al. Lieberman JM, Williams WR, Miller JM, et al. 6th ed. A special product for intravenous use — called NHIG (intravenous) — is for people who need large doses of immunoglobulin. Hoskins R, Vohra R, Vlack S, et al. Introduce the NHIG slowly into the muscle, to reduce pain. The same principle applies to the 2 MMRV vaccines,15 although they are not routinely recommended in a 2-dose schedule. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Feigin and Cherry's textbook of pediatric infectious diseases. Medical Journal of Australia 2013;198:320-3. If the lyophilized vaccine cannot be dissolved, discard. People who work in childhood education and care do not need to receive measles-containing vaccine if they have either: People who work in long-term care facilities are strongly recommended to have received 2 doses of measles-containing vaccine given at least 4 weeks apart. The fever may be associated with malaise and/or a non-infectious rash. WHO is overseeing efforts to eliminate measles worldwide through immunisation and surveillance strategies.57 After extensive vaccination campaigns, global measles deaths have decreased by 84% — from more than 550,000 in 2000 to less than 90,000 in 2016.58, In 2003, the Expanded Programme on Immunization for the WHO Western Pacific Region (WPRO) listed measles elimination as a regional goal.59 Although WPRO did not meet its 2012 target date, the measles elimination initiative led to a significant decline in cases, with the lowest level of transmission recorded in 2012.60, Plans for achieving measles control and elimination across all WHO regions are continually being developed.61,62. See also Vaccination for people who are immunocompromised.  |  Measles is a highly contagious disease that results from infection with measles virus and is still responsible for more than 100 000 deaths every year, down from more than 2 million deaths annually before the introduction and widespread use of measles vaccine. Dey A, Knox S, Wang H, Beard FH, McIntyre PB. Laboratory methods supporting measles surveillance in Queensland, Australia, 2010-2017. Lancet. Minimum acceptable age for the 1st dose of scheduled vaccines in infants in special circumstances inCatch-up vaccination. Huang GK, Bond KA, Hewitt NH, Johnson PD. All adolescents and adults born during or since 1966 should have either: About 10% of measles cases involve complications. –low levels of optimism regarding the likelihood of efficacy and low cost of development (scores around 50%); –moderate levels of optimism regarding answerability, low cost of It is characterised by: A maculopapular rash typically begins on the face and upper neck, and then becomes generalised. Prepare for vaccine administration, including storage and handling information. J Am Coll Emerg Physicians Open. Uzicanin A, Zimmerman L. Field effectiveness of live attenuated measles-containing vaccines: a review of published literature. (877.829.6372), Phone: 877.VAX.MERCK The dose of Priorix and M-M-R-II (MMR) vaccine for both children and adults is 0.5 mL given by either subcutaneous or intramuscular injection. It contains antibodies that are commonly present in adult human blood. The following people with HIV may receive MMR vaccine:18,21-25. Verstraeten T, Jumaan AO, Mullooly JP, et al. In the United States, post-marketing studies did not find an increase in fever or febrile convulsions after children received the 2nd dose of ProQuad (MMRV) vaccine. USA.gov. 160 mg/mL immunoglobulin (mainly IgG) prepared from Australian blood donations. Measles vaccines. 2012 Jul 6;30(32):4709-16. doi: 10.1016/j.vaccine.2012.04.058. The product information for Priorix, M-M-R II and Priorix-tetra states that people with a history of anaphylactic or anaphylactoid reactions to egg should not receive these vaccines. Children >12 months of age who have received 1 dose of measles-containing vaccine can receive their 2nd dose early if: If varicella vaccination is also indicated, MMRV vaccine can be used. This site is intended only for residents of the United States, its territories, and Puerto Rico.

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